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A Study of Forty Consecutive Cases of Suspected Intraocular Malignant Melanomas

ANTHONY DONN, M.D.; JOHN W. McTIGUE, M.D.

AMA Arch Ophthalmol. 1957;57(5):668-671.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Since the first report by Thomas, Krohmer, and Storaasli, in 1952,¹ many excellent studies have confirmed the fact that the measureable uptake of radioactive phosphorus is greater over malignant melanomas of the eye than over normal ocular tissue, intraocular hemorrhage, or serous retinal detachments.^2-14 A wealth of case reports in these papers documents the fact that this difference in uptake may be used clinically to distinguish a malignant melanoma from a more benign condition in the eye. As the experience with this technique has increased, however, it has also become apparent that there are three important limitations to the clinical effectiveness of this test: (1) Lesions at the posterior pole may not be accessible to the probe counter; (2) inflammatory lesions may give false-positive readings for malignant melanomas; (3) inaccuracies inherent in the counting procedure may give false results. For these reasons, a good deal of skepticism . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the Institute of Ophthalmology of the Presbyterian Hospital.

Footnotes
Received for publication Jan. 16, 1957.

This study was supported by Grant 156 from the National Council to Combat Blindness.

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