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G. P. M. HORSTEN, M.D.; J. E. WINKELMAN, M.D.

AMA Arch Ophthalmol. 1957;57(4):557-565.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

During clinical electroretinographic examination of patients we observed a new phenomenon which we called "exhaustion phenomenon" (phénomène d'épuisement). This phenomenon has been further studied in cats.

Briefly, it is as follows: If the darkadapted cat retina is stimulated intermittently with light of 50 lux intensity (measured at the cornea), one-tenth second duration, and one second frequency, the b-potential in the ERG is practically the same for each stimulus. If, however, the procedure is repeated on a cat with impaired oxygen supply, the b-potentials on intermittent stimulation become progressively smaller and finally may almost disappear. If the intermittent stimulation is now suspended for a time, e. g., one minute, while the cat still remains in darkness, the b-potential will be found to have returned to its former level, but on intermittent stimulation it will again become smaller. We ascribed this phenomenon to a delayed recovery of the adaption state in hypoxemia. . . . [Full Text PDF of this Article]

Author Affiliations
Amsterdam, Netherlands

From the physiological laboratory of the Roman Catholic University of Nijmegen (Director, Prof. Dr. Horsten) and the eye clinic of the University of Amsterdam (Director, Prof. Dr. A. Hagedoorn).

Footnotes
Received for publication Aug. 6, 1956.

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