This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (32)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

II. Control of Corneal Size

ALFRED JOSEPH COULOMBRE, Ph.D.

AMA Arch Ophthalmol. 1957;57(2):250-253.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

The increase in size of the vertebrate eye as a whole is regulated by a number of factors. Thus, the results of heteroplastic transplantations of amphibian eye priomordia by Harrison¹ and Twitty and Schwind² have implicated genetic factors. In addition to genetic factors, nutritional factors may influence the enlargement of the amphibian globe.^3,4 Recent work with the chick embryo has revealed two additional factors. Not only is intraocular (vitreal) pressure a cardinal factor influencing the increase in the size of the eye, as shown by Weiss and Amprino⁵ and me,^6,7 but the resistance to expansion offered by the eye wall as it elaborates cartilage and collagen appears to be important in progressively decreasing the rate of ocular expansion as development proceeds.⁷

If we turn our attention from the eye as a whole to its parts, we find much observational and experimental work supporting . . . [Full Text PDF of this Article]

Author Affiliations
New Haven, Conn.

Department of Anatomy, Yale University School of Medicine.

Footnotes
Received for publication Sept. 24, 1956.

This investigation was supported in part by a research grant (B-870) from the National Institute of Neurological Diseases and Blindness of the National Institutes of Health, Public Health Service, and in part by a grant from the James Judson Brown Memorial Fund of Yale University School of Medicine.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?