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H. KARL BOYER, Ph.D.; ANITA A. SURAN, M.S.; MICHAEL J. HOGAN, M.D.; WILLIAM K. McEWEN, Ph.D.

AMA Arch Ophthalmol. 1956;56(6):861-864.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It seems to be accepted¹ that if the volume of the eye increases during pathological growth, such as in myopia, the increased space is not filled with normal gel-like vitreous but rather with a "liquid vitreous." Our interest has been to determine whether, during normal growth, the increased volume of the eye is occupied by a gel-like vitreous or by the secretion of a "liquid vitreous" into a preformed residual protein structure. It has been reported by Bembridge and Pirie² that the rabbit probably commences to secrete hyaluronic acid into the vitreous only after birth. Balazs³ indicates that the vitreous hyaluronic acid and ascorbic acid contents parallel the increase in the vitreous during growth, while calcium and the soluble proteins of the vitreous decrease slightly from birth to adulthood. Information is not available pertaining to the rate of formation of the residual protein.

This report attempts to . . . [Full Text PDF of this Article]

Author Affiliations
San Francisco

Francis I. Proctor Foundation for Research in Ophthalmology, University of California Medical Center.

Footnotes
Received for publication June 29, 1956.

The investigations of which this paper is a part are based on work performed under Contract DA-49-007-MD-394 of the Department of the Army and under a research grant, B-180, from the National Institute of Neurological Diseases and Blindness of the National Institutes of Health, Department of Health, Education, and Welfare.

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