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ANDREW S. WONG, M.D.; ROCKO M. FASANELLA, M.D.; LEANOR D. HALEY, Ph.D.; CARTER L. MARSHALL, M.D.; WILLARD A. KREHL, Ph.D.

AMA Arch Ophthalmol. 1956;55(2):246-253.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

INTRODUCTION

The widespread prevalence of blepharitis marginalis, described by Duke-Elder¹ as "a subacute or chronic inflammation of the margins of the lids," is well known. Its etiology is both complex and manifold and has not been conclusively defined.

Classically, this condition can be divided into two broad categories: (1) simple squamous blepharitis and (2) ulcerative blepharitis. The first reflects hyperemia, congestion, and edema of the lid margins with a consequent scaling of the lids. The latter involves the ciliary follicles and associated sebaceous glands of Zeis and sweat glands of Moll. At first, suppurative abscesses develop intrafollicularly, followed by more extensive destructive inflammation and subsequent scarring.

The usual complications which follow include chronic conjunctivitis, hordeolum, chalazion, ectropion, entropion, trichiasis, and keratitis.

The principal causes to which blepharitis has been attributed * may be classified as those stemming from (1) predisposing factors, including eyestrain, metabolic disorder, vitamin deficiency, and heredity; (2) . . . [Full Text PDF of this Article]

Author Affiliations
New Haven, Conn.

From the Section of Ophthalmology, Department of Surgery, Yale University School of Medicine.

Footnotes
Submitted for publication Dec. 5, 1955.

The investigative work was made possible by grants from the Medical Fluid Research Fund, Yale University School of Medicine. Grateful acknowledgment is made to Mr. Arnold E. Osterberg, Abbott Laboratories, North Chicago, Ill., from whom preparations of Selsun Jelly were obtained. Assistance was received from Miss Mary Stonerod, Chief Technologist, Mycology Laboratory, and Dr. Maurice Van Lonkhyzen and Dr. Bernard Zuckerman, Residents in Ophthalmology.

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