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Clinicopathologic Report of a Case

MANOS A. PETROHELOS, M.D.; J. REIMER WOLTER

AMA Arch Ophthalmol. 1956;55(2):221-228.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Necroscleritis nodosa, a degenerative condition of the sclera of unknown etiology, has only recently been recognized as a clinical entity. Its pathologic characteristics are as yet not sufficiently known to enable the ophthalmologist to differentiate this disease from brawny scleritis or scleromalacia perforans.

HISTORICAL BACKGROUND

Van der Hoeve (1930) presented before the Dutch Ophthalmological Society two cases of a new degenerative entity of the sclera which he named scleromalacia perforans. The same author,¹ in 1934, reported in more detail two of Rochat's cases² and two of his own. Verhoeff and King³ and, more recently, Franceschetti and Bischler⁴ clarified this constitutional entity. They emphasized its differential diagnosis and separated it from simulating scleral diseases. Franceschetti suggested that the term perforating scleromalacia should be reserved for cases with little or no inflammatory reaction and associated with rheumatoid arthritis. The term nodular necrotizing scleritis, on the other hand, was . . . [Full Text PDF of this Article]

Author Affiliations
Ann Arbor, Mich.

Department of Ophthalmology (Dr. Petrohelos) and Laboratory of Neuropathology and Neuro-Ophthalmology (Dr. Wolter), Neuropsychiatric Institute, University Hospital.

Footnotes
Received for publication Sept. 21, 1955.

This study was supported in part by a grant-inaid from the U. S. Department of Public Health, Education, and Welfare.

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