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  Vol. 53 No. 4, April 1955 TABLE OF CONTENTS
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Studies on experimental Glaucoma

ENRIQUE WUDKA, M.D.; IRVING H. LEOPOLD, M.D.

AMA Arch Ophthalmol. 1955;53(4):487-494.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The aim of the present investigation is the study of experimentally induced glaucoma in the rabbit and the influence of iridectomy on its course. The normal intraocular pressure can be raised (a) by decreasing the aqueous drainage or (b) by increasing the rate of fluid production.

  1. Diminished aqueous outflow has been achieved by mechanical blockage of the filtration angle. This can be accomplished in the following ways: (a) by injecting oils and colloids that hinder the outflow of aqueous at the angle of the anterior chamber1; (b) by producing an inflammatory response at the angle, with ultimate development of synechiae1; (c) by developing a proliferative endothelial reaction at the angle by means of electrolytic products,1 and (d) by occlusion of the pupil, which also leads to mechanical blockage of the angle of the anterior chamber. Interruption of the aqueous circulation at the pupil has been produced by obstructing
. . . [Full Text PDF of this Article]


Author Affiliations

Philadelphia

From the Research Department of Wills Eye Hospital.



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