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  Vol. 51 No. 4, April 1954 TABLE OF CONTENTS
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THREE NEW CYCLOPLEGIC DRUGS

Clinical Report

BERNARD C. GETTES, M.D.

AMA Arch Ophthalmol. 1954;51(4):467-472.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

O F A GROUP of new parasympathomimetic-blocking agents, three appear to be effective cycloplegic drugs suitable for refraction. These compounds are esters of disubstituted acetic acids (Treves and Testa*; Ehrenberg, Ramp, Blanchard, and Treves {dagger}). These drugs have been reported as cyclopentolate {ddagger} (Compound 75 GT), Compound 92 GT and Compound 93 GT. Their usage in 0.5% solution has been previously reported (cyclopentolate, by Priestley and Medine,2 and all three compounds by Gettes and Leopold3 and by Stolzer4). Their cycloplegic efficiency appeared greater than that of homatropine but not quite as great as that of atropine. In addition, they possess the advantage of a shorter duration of activity and an absence of local or systemic reactions. This report concerns the study of the effect of 1% solutions of the same preparations.

Formula

Two per cent solutions were also employed, but in this concentration these compounds were found to . . . [Full Text PDF of this Article]


Author Affiliations

PHILADELPHIA


Footnotes

Read before the Section on Ophthalmology at the 102nd Annual Meeting of the American Medical Association, New York, June 3, 1953.

Assistant Professor in Ophthalmology, University of Pennsylvania Graduate School of Medicine; Chief, Refraction Department, and Assistant Surgeon, Wills Eye Hospital.



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