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ADULT OCULAR TOXOPLASMOSISA Preliminary Report of a Parasitologically Proved Case
LEON JACOBS;
MAJOR JOHN R. FAIR;
MAJOR JOHN H. BICKERTON
AMA Arch Ophthalmol. 1954;51(3):287.
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AFTER the report of Wilder1 (1952) of the finding of organisms resembling Toxoplasma by microscopic examination of chorioretinal lesions in over 50 cases of inflammatory eye disease, a collaborative study on toxoplasmosis has been conducted by the Ocular Research Unit of Walter Reed Army Medical Center and the Laboratory of Tropical Diseases, National Microbiological Institute. The purpose was to identify by other means the organism seen by Wilder and to ascertain the importance of the parasite as an etiological agent of uveitis.
It became apparent in this and other studies that it was not possible merely by serological means to establish unequivocally the identity of the parasite. The high prevalence of serological evidence of past Toxoplasma infection in the general population of the areas studied prevented a positive diagnosis in the individual case. It was recognized that a combination of clinical, parasitological, and pathological evidence would be necessary to
. . . [Full Text PDF of this Article]
Author Affiliations
SENIOR SCIENTIST, UNITED STATES PUBLIC HEALTH SERVICE; MEDICAL CORPS, UNITED STATES ARMY; MEDICAL CORPS, UNITED STATES AIR FORCE
From the United States Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Microbiological Institute, Bethesda 14, Md. (The work was supported in part by the National Institute of Neurological Diseases and Blindness.)
Footnotes
Armed Forces Institute of Pathology, Washington, D. C. (Major Bickerton).
Ocular Research Unit, Walter Reed Army Medical Center, Washington, D. C. (Major Fair).
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