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  Vol. 50 No. 4, October 1953 TABLE OF CONTENTS
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HEREDITARY POLYMORPHOUS DEEP DEGENERATION OF THE CORNEA

HARRY B. McGEE, M.D.; HAROLD F. FALLS, M.D.

AMA Arch Ophthalmol. 1953;50(4):462-467.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT HAS been our privilege to study two families certain members of which exhibited a rarely observed form of endothelial dystrophy of the cornea. A careful survey of the families revealed that the aberration is hereditary and most likely congenital. It is to be differentiated from the usually described endothelial dystrophy, or corneal guttata.

REVIEW OF LITERATURE

Polymorphous degeneration of the deep layers of the cornea is characterized by the presence of polymorphic opacities, vesicles, and concavities of the endothelium, and possibly Descemet's membrane.

Koeppe1 (1916) was probably the first to describe this form of endothelial dystrophy. He presented six cases of his own in which keratitis bullosa interna was exhibited. This author postulated that the concavities were congenital pits on the inner corneal surface. In 1920 Koeppe reported 18 cases in which similar lesions were present. Since the eyes exhibited no other pathologic condition, the author concluded that . . . [Full Text PDF of this Article]


Author Affiliations

ANN ARBOR, MICH.

Junior Clinical Instructor, Department of Ophthalmology (Dr. McGee).; Associate Professor of Ophthalmology and Research Associate of Institute of Human Biology, University of Michigan (Dr. Falls).



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