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J. V. CASSADY, M.D.; CARL S. CULBERTSON, M.D.

AMA Arch Ophthalmol. 1953;50(1):68-74.

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THE ETIOLOGY of Parinaud's oculoglandular syndrome has always been an enigma. In some cases the syndrome has been associated with tularemia; in many with leptothricosis, and in a few, with syphilis, tuberculosis, or sporotrichosis. In a large number of cases, however, a thorough search for an inciting factor has been of no avail, and the origin of the disease is surrounded with much uncertainty. Numerous reports concerning cat-scratch disease have appeared in the recent medical literature. In many instances Parinaud's oculoglandular syndrome is probably a form of the same disease entity in which the etiologic agent has gained entrance into the conjunctiva rather than into the skin.

In 1889 Parinaud¹ described cases of oculoglandular fever starting as conjunctivitis with granulations, associated with enlargement of regional lymph nodes and a moderate fever, which persisted for weeks. He believed that this disease was contracted from animals. Gifford,² in 1898, gave . . . [Full Text PDF of this Article]

Author Affiliations
SOUTH BEND, IND.

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