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MAX FINE, M.D.; RUFUS C. GOODWIN, M.D.

AMA Arch Ophthalmol. 1952;47(6):787-797.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE OBSERVATION that the hormone cortisone exerts a remarkable therapeutic effect on certain inflammations of the eye is one of the most important contributions to ophthalmologic therapy in a decade which has witnessed many revolutionary discoveries. The further observation that this hormone is effective by local application, topically, subconjunctivally, or by retrobulbar injection, has already made its use more widespread in ophthalmology than in any other branch of medicine. In its local application the many hazardous metabolic side-effects are avoided, since the dose required is minute as compared with that required for its systemic administration. For the same reason, the temporary scarcity of the drug has not limited its use in the eye to the same extent that it has in other fields.

Leopold and his co-workers¹ have confirmed experimentally what was already quite certain clinically, namely, that cortisone applied locally penetrates the eye to produce therapeutic concentrations in . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Division of Ophthalmology, Department of Surgery, Stanford University School of Medicine, and the Veterans Administration Hospital.

Footnotes
The Staff of Letterman General Hospital, United States Army, permitted us to study the traumatic cases.

Presented in part at a symposium on corticotropin (ACTH) and cortisone in Ophthalmology, Section on Eye, Ear, Nose and Throat, San Francisco County Medical Society, April 26, 1951.

Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions presented by the authors are the result of their own studies and do not necessarily reflect the opinion or policy of the Veterans Administration.

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