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NICHOLAS G. DOUVAS, M.D.; ROBERT M. FEATHERSTONE, Ph.D.; ALSON E. BRALEY, M.D.

AMA Arch Ophthalmol. 1951;46(1):57-68.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

WITH THE discovery of new antibiotic substances the treatment of ocular diseases has changed considerably during recent years. One of the new broad bacterial spectrum antibiotics is terramycin.¹ This antibiotic will be compared with previously reported substances to determine its role in ophthalmology.²

Terramycin is an amphoteric compound whose empirical formula is believed to be C₂₂H_22-24N₂O₉ · 2H₂O.³ The chemical and physical properties of terramycin have been studied,⁴ as well as its antimicrobial action⁵ and pharmacodynamics.⁶ Numerous articles on the clinical effectiveness of terramycin in a wide variety of infections have appeared in the literature.⁷ At the time of this writing no published reports are available on the effectiveness of terramycin in the treatment of ocular infections.

Terramycin hydrochloride, powdered and in a special ophthalmic borate buffer, and 0.1 per cent terramycin hydrochloride in . . . [Full Text PDF of this Article]

Author Affiliations
IOWA CITY

From the Departments of Ophthalmology and Pharmacology, the State University of Iowa College of Medicine.

Footnotes
This manuscript has been submitted by Dr. Douvas to the Graduate College of the State University of Iowa in partial fulfilment of the requirements for the degree of Master of Science in Ophthalmology.

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