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PAUL HURWITZ, M.D.; JOHN M. THOMPSON, M.D.

Arch Ophthal. 1950;43(4):712-717.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

NAPHAZOLINE hydrochloride (privine®; 2-[1-naphthyl-methyl]-imidazoline hydrochloride) has long been in use as a nasal decongestant. Heretofore, however, it has not been used in ophthalmology in this country. Since its properties indicate potential usefulness as an ocular decongestant, it was decided to determine its value in a number of clinical conditions. It became evident that naphazoline hydrochloride in ophthalmic solution could be a valuable adjunct to the ophthalmologic armamentarium. Hence a series of experiments was conducted to determine the effect of naphazoline on intraocular tension, pupillary size, accommodation and status of the ocular blood vessels.

Naphazoline hydrochloride¹ in 0.1 per cent ophthalmic solution has the following formula:

CLINICAL APPLICATION

Babel² and Fanta³ reported on the effect of naphazoline on the eyes of rabbits and human subjects. In view of the contemplated manufacture of privine® ophthalmic solution for the commercial market, it was deemed advisable to publish the results of . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO; SOUTH BEND, IND.

Footnotes
The experimental phase of this work was done at the University of Illinois, Department of Ophthalmology (Illinois Eye and Ear Infirmary), Chicago.

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