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EARLY DIAGNOSIS OF SYPHILITIC PRIMARY OPTIC NERVE ATROPHY
JOSEPH V. KLAUDER, M.D.;
GEORGE P. MEYER, M.D.
Arch Ophthal. 1950;43(3):537-552.
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IN A PREVIOUS communication1 a study of 397 patients with syphilitic primary optic nerve atrophy was presented. The visual acuity of 61 per cent of these patients when they were first seen was less than 6/60 in both or in the better eye (in 44 per cent it was 1/60 to 6/60, and in 17 per cent it was less than 1/60). This constitutes industrial blindness and represents an unfortunate experience in the early diagnosis of syphilitic optic nerve atrophy among the ward and clinic patients at Wills Hospital.
Our purpose in the present paper is to discuss the earliest signs of syphilitic optic nerve atrophy, the prodromal symptoms and the pitfalls in early diagnosis.
Pertinent data in the study of our 397 patients in relation to early diagnosis are concerned with the following points: 1. The occurrence of optic nerve atrophy in patients whose early syphilis was untreated.
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA; CAMDEN, N. J.
From the Clinic for Treatment of Ocular Syphilis, Wills Hospital.
Footnotes
Read at the First Annual Clinical Conference of Wills Hospital, May 6, 1949.
The work described in this paper was done under a contract recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the Wills Hospital, and later under a grant-in-aid from the Research Grants and Fellowship Division, National Institute of Health, United States Public Health Service.
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