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LUDWIG von SALLMANN, M.D.; TITUS C. EVANS, Ph.D.; BEATRICE DILLON, M.A.

Arch Ophthal. 1949;41(5):611-626.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ARTIFICIAL radioactive isotopes were introduced for turn-over studies on the eye by Kinsey, Grant, Cogan, Livingood and Curtis.¹ These investigators used Na²⁴, P³² and Cl³⁸ in their work with rabbits. Recently, Wang² studied the movement of radioactive sodium and chloride in dogs, whereas Visscher and Carr³ (in dogs) and Scholz, Wilde and Cowie⁴ (in guinea pigs) limited their study to radiosodium. These investigations revealed the steady state ratios of the tracer elements between plasma and ocular fluids and the turnover rates of these constituents in the aqueous humor. The investigations of Visscher and Carr³ and Wang² included studies on the rate of entrance of the radioactive elements into the cerebrospinal fluid. All these results confirmed the impression of the usefulness of radioactive elements as tracers in biologic studies. Quantitative data of great accuracy were secured by measuring (with the Geiger-Müller counter) . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Ophthalmology and the Department of Radiology, Columbia University College of Physicians and Surgeons.

Footnotes
Supported by the Knapp Memorial Foundation.

Read in part at the Three Hundred and Eighty-First Meeting of the New England Ophthalmological Society, Boston, Feb. 18, 1948.

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