This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (3)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

David G. Cogan, M.D.; W. Morton Grant, M.D.
Boston.

Howe Laboratory of Ophthalmology, 243 Charles Street.

Arch Ophthal. 1947;38(6):847.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editors:

—In connection with Dr. Banks Anderson's article, entitled "Corneal and Conjunctival Pigmentation Among Workers Engaged in the Manufacture of Hydroquinone," which appears in this issue of the ARCHIVES, it may be of interest to note our unsuccessful attempts in the Howe Laboratory to produce pigmentation of the cornea and conjunctiva in rabbits and guinea pigs by acute exposure to parabenzoquinone vapor. This is the compound presumably responsible for the pigmentation in human beings. Three albino rabbits and 6 guinea pigs were introduced into an exposure chamber containing solid quinone spread out on a tray, but separated from contact with the animals. The concentrations of parabenzoquinone vapor in the chamber at various times were as low as 2 parts, and as high as 13 parts, per million. The concentration in the plants where Anderson's patients worked varied between 0.01 and 3.2 p.p.m.¹

The animals were examined after . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?