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Conjunctival Changes

BENJAMIN FRIEDMAN, M.D.

Arch Ophthal. 1947;38(6):796-805.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CASES of severe sulfadiazine poisoning have occurred during the course of mass prophylaxis in military personnel, but they have been relatively infrequent. Even these cases ought to be fewer, for the supervising physician has become more aware of the possibility of untoward effects and has trained himself to recognize early the symptoms of idiosyncrasy to sulfadiazine. Serious sulfadiazine poisoning is of three types: that in which the picture of agranulocytosis predominates, that which is associated with urinary suppression and that which presents widespread mucocutaneous pemphigoid lesions. I observed 3 cases of the last type at a Naval training center and found them of special ophthalmologic interest because of the characteristic conjunctival lesions which were exhibited. The systemic reactions varied in these cases, the first patient being moderately ill, the second severely ill and the third critically ill. The severity of the conjunctival lesions paralleled the general clinical course. Because of . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

Footnotes
Read at a meeting of the New York Academy of Medicine, Section of Ophthalmology, Nov. 18, 1946. A discussion on this paper was published in the May 1947 issue of the Archives, page 694.

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