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  Vol. 32 No. 4, October 1944 TABLE OF CONTENTS
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CARBAMINOYLCHOLINE CHLORIDE IN THE TREATMENT OF GLAUCOMA

DANIEL KRAVITZ, M.D.

Arch Ophthal. 1944;32(4):283-286.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Until the causes are found, glaucoma, acute and chronic, will be a never ending source of worry to the ophthalmologist, as well as to the patient. The results, even with the best of therapy, all too often are disastrous. Ophthalmologists are therefore on a continuous lookout for new therapeutic methods, both medical and surgical.

In the last few years the greatest advance in the medical treatment of glaucoma has been the synthesis of a large group of cholinergic drugs : mechylol, neostigmine, furfuryltrimethylammonium iodide and, the latest, carbaminoylcholine chloride.

Carbaminoylcholine chloride is a synthetic choline derivative which acts principally by inducing parasympathetic stimulation. Its chemical structure is similar to acetylcholine ; and, according to O'Brien and Swan,1 its action is more prolonged because its hydrolysis is slow and it is therefore more stable in the tissues. Used experimentally on isolated sphincter of the iris, it is one of the most powerful . . . [Full Text PDF of this Article]


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BROOKLYN



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