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HAROLD G. SCHEIE, M.D.; ELINOR MOORE, Ph.D.; FRANCIS H. ADLER

Arch Ophthal. 1943;30(1):70-74.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It has been established that the aqueous humor contains less urea than the circulating blood. Urea should be present in equal amounts in aqueous and blood if the aqueous is formed by dialysis alone, since urea is a crystalloid and a nonelectrolyte. It is, however, possible that after the aqueous is formed other processes alter its chemical composition so that it can no longer be recognized as a dialysate. In an attempt to explain this discrepancy a number of factors were explored and reported in a previous paper.¹

As a result of those studies the low urea content of aqueous was attributed to a lack of permeability of the blood-aqueous barrier to urea. Under normal conditions the membrane separating aqueous from blood does not allow urea to pass through it readily, so that the concentration is always about 20 per cent less in aqueous than in blood. This is . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Department of Ophthalmology, University of Pennsylvania School of Medicine.

Footnotes
This work was made possible by a grant from the John and Mary R. Markle Foundation.

Read at the Seventy-Eighth Annual Meeting of the American Ophthalmological Society, Hot Springs, Va., June 2, 1942.

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