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III. SLIT LAMP STUDIES OF THE CONJUNCTIVAL REACTIONS INDUCED IN NORMAL AND IN ATOPIC PERSONS WITH HISTAMINE, ETHYLMORPHINE AND ATOPENS

LOUIS A. FELDMAN, M.D.; HYMAN SHERMAN, M.D.

Arch Ophthal. 1943;29(6):989-995.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The skin presents obvious obstacles to a satisfactory study of the detailed changes which occur in the vascular responses involved in specific and nonspecific wheal formation. The accessibility of the ophthalmic mucosa, with its visible blood supply, suggested the conjunctiva as an ideal site for the study of vascular reactions resulting from excitation with immunologic and nonspecific agents. With the aid of the slit lamp miscroscope, studies were undertaken to compare the characteristics of the specific and of the nonspecific reactions.

The ability of certain substances, antigenic and nonantigenic, to produce a conjunctival reaction is well known. Pollen extracts and other allergens almost regularly produce ophthalmic reactions in persons sensitive to them. Histamine and ethylmorphine, because of their ability to induce dilatation of the conjunctival vessels and even edema, are examples of nonspecific substances capable of eliciting a conjunctival reaction. Ethylmorphine, a derivative of morphine, is a vasodilator and lymphagogue. . . . [Full Text PDF of this Article]

Author Affiliations
BROOKLYN

From the Ophthalmology and Allergy Services of the Jewish Hospital.

Footnotes
Presented at the fourth semiannual meeting of the Division of Allergy of the Jewish Hospital.

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