This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

MAJOR PHILLIPS THYGESON

Arch Ophthal. 1943;29(6):1000-1022.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since 1937 the sulfonamide compounds have been employed with success in the treatment of an increasing number of ocular infections, and an extensive literature has already accumulated in the few years since their introduction. In the present review I have attempted to summarize the significant literature and to evaluate in the light of available laboratory studies and personal experience the sometimes conflicting clinical results reported.

SULFONAMIDE COMPOUNDS AVAILABLE FOR CLINICAL USE

Since the introduction of the original prontosil by Domagk¹ in 1935, a large number of related compounds have been tested experimentally, but only a few have been found suitable for clinical use. In the United States only azosulfamide, sulfanilamide, sulfapyridine (2-[paraaminobenzenesulfonamido]-pyridine), sulfathiazole (2-[paraaminobenzenesulfonamido]-thiazole) and sulfadiazine (2-[paraaminobenzenesulfonamido]-pyrimidine) have come into general use in the treatment of ocular infections. Of these, azosulfamide and sulfapyridine have now been virtually discarded, the former because it is believed to have no action other . . . [Full Text PDF of this Article]

Author Affiliations
MEDICAL CORPS, ARMY OF THE UNITED STATES

From the Department of Ophthalmology, Columbia University College of Physicians and Surgeons, and the Institute of Ophthalmology, Presbyterian Hospital.

Footnotes
Read in part before the Pacific Coast Oto-Ophthalmological Society, Portland, Ore, May 12, 1942.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?