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  Vol. 29 No. 5, May 1943 TABLE OF CONTENTS
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IONTOPHORETIC INTRODUCTION OF ATROPINE AND SCOPOLAMINE INTO THE RABBIT EYE

LUDWIG VON SALLMANN, M.D.

Arch Ophthal. 1943;29(5):711-719.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Repeated attempts were made to introduce the common mydriatics employed in ophthalmology by means of a galvanic current1 because an increased activity of these drugs is desirable in a number of pathologic conditions of the eye. Rochatla studied the iontophoretic administration of atropine and other alkaloids in experiments on rabbits and by clinical observation. When other clinical methods had failed, he demonstrated the effectiveness of the iontophoretic method in breaking resistant posterior synechias despite the low concentration of the atropine sulfate solution (0.1 per cent). Rochat based his conclusions on measurements of the pupils of treated eyes. He did not consider, however, the effect of electric current per se, which increases or decreases the size of the pupil in different degrees according to the strength of the current and the length and method of application. Quantitative determinations of the mydriatics found in different parts of the eye after . . . [Full Text PDF of this Article]


Author Affiliations

NEW YORK

From the Department of Ophthalmology, Columbia University College of Physicians and Surgeons, and the Institute of Ophthalmology, Presbyterian Hospital.


Footnotes

Supported by the Knapp Memorial Foundation.



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