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  Vol. 29 No. 4, April 1943 TABLE OF CONTENTS
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ROLE OF ASCORBIC ACID (VITAMIN C) IN SECRETION OF INTRAOCULAR FLUID

JONAS S. FRIEDENWALD, M.D.; WILHELM BUSCHKE, M.D.; HARRY O. MICHEL, Ph.D.

Arch Ophthal. 1943;29(4):535-574.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

OUTLINE

  1. Introduction
  2. Redox substances in the ciliary body
    1. Titration and identification
      1. Technic
      2. Results
      3. Summary

    2. Location of redox substances in the tissues
      1. Ascorbic acid
      2. Glutathione
      3. Summary


  3. Ascorbic acid in the mechanism of secretion of intraocular fluid
    1. Redox substances in the ocular tissues of guinea pigs
    2. Oxidation-reduction potential
    3. Irreciprocal permeability to dyes
    4. Transfer of water

  4. Mechanism of storage of ascorbic acid
  5. Intraocular secretion of ascorbic acid
  6. Intraocular secretory systems without ascorbic acid
  7. Comment
  8. Summary

INTRODUCTION

In a previous paper1 certain components of the secretory mechanism in the ciliary body were described and a theory was formulated to explain their interaction. The present study is a continuation of the same investigation. Ascorbic acid (vitamin C) is a substance derived from the blood but present in the intraocular fluid in a concentration appreciably higher than in the blood.2 Energy must be expended by the tissues to maintain the difference in concentration. The . . . [Full Text PDF of this Article]


Author Affiliations

BALTIMORE

From the Wilmer Ophthalmological Institute of the Johns Hopkins University and Hospital.


Footnotes

This investigation was supported in part by a grant from the John and Mary R. Markle Foundation. The work was presented in part before the American Ophthalmological Society June 7, 1939.



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