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EDWARD HARTMANN, M.D.

Arch Ophthal. 1942;28(4):599-612.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

ACETYLCHOLINE IN OPHTHALMOLOGY

Acetylcholine was first prepared in 1867 by Baeyer,¹ but it was not until 1906 that Hunt and Taveau² discovered its action on the circulation. Another twenty years passed before the drug was clinically investigated by Villaret and Justin-Besançon;³ I believe it was first used by them in 1926 in a case of Raynaud's disease. During the next fifteen years it was widely used in France, and like most new medicines it went through an initial period when it was tried in the treatment of various diseases and a second one when the boom was over and when experience had shown in what diseases and in what selected cases it could be helpful.

Pharmacodynamics.⁴

—Acetylcholine derives from choline and is normally found in many tissues of the body, as it is liberated at the nerve endings in vagal or parasympathetic nerve impulses. Inversely, the . . . [Full Text PDF of this Article]

Author Affiliations
RIVERDALE, N. Y.

Not in practice.

Footnotes
Read before the Section of Ophthalmology of the New York Academy of Medicine, Dec. 15, 1941.

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