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WILLIAM F. HUGHES, Jr., M.D.

Arch Ophthal. 1942;27(3):582-601.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

OUTLINE

1. Incidence
   
2. Dose necessary to produce lesion
   
3. Course of severe corneal burns
   
4. Action on tissue
   
   1. Local Action
      
      1. Liberation of hydrochloric acid
         
      2. Derivatives
         
      3. Whole molecule
         
      4. Tissue hypersensitivity
         
      
      
   2. Systemic Action
      
      1. Break-down products
         
      2. Metabolism
         
      3. Bone marrow
         
      4. Antibodies
         
      5. Changes secondary to burns
         
      6. Fundus changes
         
      
      
   
   
5. Prophylaxis
   
6. Treatment
   
   1. Patients without corneal involvement
      
      1. Reassurance
         
      2. Irrigations Bland solutions Hypertonic solutions Neutralizing agents Irrigating apparatus
         
      3. Dark glasses or eye shade
         
      4. Convalescence
         
      
      
   2. Patients with corneal involvement
      
      1. Immediate treatment
         
      2. Oily drops and ointments
         
      3. Ascorbic acid
         
      4. Secondary infections Mild silver protein and boric acid Antiseptics Sulfanilamide and derivatives
         
      5. Convalescence
         
      6. Late treatment
         
      
      
   
   
7. Summary of present treatment
   

Author Affiliations
BALTIMORE

From the Wilmer Ophthalmological Institute of Johns Hopkins University and Hospital.