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CLARENCE A. VEASEY, Jr., M.D.

Arch Ophthal. 1941;25(3):450-468.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The vitamin B complex is a group of water-soluble substances necessary in minute quantities for health and growth in man and in other animals. Some of these substances have been identified chemically ; the existence of others is predicated on disease in laboratory animals fed deficient diets. At present the following components have been identified or are presumed to exist:

Thiamine (or vitamin B₁) is the antineuritic and beriberi-preventing vitamin. It acts as a catalyst in the combustion of carbohydrate, which in its absence is arrested at the pyruvic acid stage, the metabolite having a toxic effect on nerve tissue. Thiamine deficiency in man causes a noninflammatory peripheral neuritis and paralyses, but not nerve degeneration. The neuritis is most apt to occur in the presence of noxious substances, such as alcohol, an elevated concentration of blood sugar or the toxins associated with toxemia of pregnancy. Gastrointestinal symptoms, including hypermotility, hypomotility . . . [Full Text PDF of this Article]

Author Affiliations
SPOKANE, WASH.

Footnotes
Condensed from a candidate's thesis submitted to the American Ophthalmological Society in August 1939. For a full discussion of the chemistry and the general clinical and experimental aspects of vitamin B, with bibliography, the reader is referred to the original article in the Transactions of the American Ophthalmological Society for 1940.

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