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  Vol. 22 No. 3, September 1939 TABLE OF CONTENTS
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DETERMINATION OF SULFANILAMIDE IN AQUEOUS AND VITREOUS AFTER CONJUNCTIVAL AND ORAL ADMINISTRATION

WILLARD G. MENGEL, M.D.

Arch Ophthal. 1939;22(3):406-409.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Sulfanilamide (paraaminobenzenesulfonamide) has been used extensively for systemic infections of various types and has been especially valuable when streptococci, pneumococci and gonococci were found. Prior to 1936 there was no mention of sulfanilamide in the ophthalmic literature, but recently numerous papers have appeared relating to this drug. Reports on the value of sulfanilamide in ocular infections have been made by L. J. and R. F. Fernandez,1 Rambo,2 Mullen and others. Engelfried3 reported that after the oral administration of sulfanilamide to rabbits the drug was found to be widely diffused throughout the body. Rambo found sulfanilamide in the aqueous, lens and vitreous of rabbits' eyes ; he reported the beneficial effect of the drug when cultures of hemolytic streptococci were injected into the vitreous and aqueous of rabbits' eyes. However, a search of the available literature revealed no reports on the determination of sulfanilamide in the aqueous and vitreous . . . [Full Text PDF of this Article]


Author Affiliations

PHILADELPHIA


Footnotes

Read before the College of Physicians, Philadelphia, Section on Ophthalmology, March 16, 1939.

This report is from the service of Dr. J. Milton Griscom, attending surgeon to the Wills Hospital.



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