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PHILLIPS THYGESON, M.D.

Arch Ophthal. 1939;21(2):229-234.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The trachoma virus is not yet known with certainty to have been grown in tissue culture. The experiments of Rumyantsev and Levkoeva,¹ of Schmidt² and of Harrison and Julianelle³ were unsuccessful. Poleff⁴ reported finding in cultures of trachomatous tissues rickettsia-like bodies which he considered to be the causal agent, but he failed to demonstrate infectivity of the cultures by inoculation of the monkey or human conjunctiva. In view of the probable nonspecific nature of these rickettsia-like bodies, which I⁵ believe to have been cellular débris, it seems probable that Poleff failed to cultivate the agent. More recently, Rötth,⁶ in a report before the Fifteenth International Ophthalmologic Congress at Cairo, Egypt, stated that he had obtained Halberstädter-Prowazek inclusion bodies in a single culture of human fetal conjunctival epithelium inoculated with an Elford filtrate of trachomatous material. Before drawing conclusions as to the value of this . . . [Full Text PDF of this Article]

Author Affiliations
With the Technical Assistance of Nancy Roberts NEW YORK

From the Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, and the Institute of Ophthalmology, Presbyterian Hospital.

Footnotes
Aided by grants from the Proctor Fund and the Committee on Scientific Research of the American Medical Association.

This study was made in cooperation with the Health Division, Office of Indian Affairs, Department of the Interior, Washington, D. C.

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