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FURTHER OBSERVATIONS

JOSEPH LEVINE, M.D.

Arch Ophthal. 1935;14(4):554-556.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In a previous issue of the ARCHIVES¹ appeared my first report on the advantages of Coley's mixed toxins as a foreign protein in ophthalmologic therapy. In that article a résumé of the history of foreign protein therapy was given, and the various proteins used in ophthalmologic practice were discussed.

What is the preparation known as Coley's mixed toxins? It is a vaccine made from killed cultures of Streptococcus erysipelatis and Bacillus prodigiosus. It is in extremely concentrated form, a red-colored fluid put up in rubber-capped glass vials of 1 cc. and 15 cc. capacity by Parke-Davis and Company. It keeps well in an icebox, and the expiration date printed on each vial can be ignored, as the fluid does not lose its efficiency over a period of several years.

How is it administered? These mixed toxins are given intramuscularly, and the deltoid muscle is used . . . [Full Text PDF of this Article]

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NEW YORK

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