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PHILLIPS THYGESON, M.D.

Arch Ophthal. 1934;12(3):307-318.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Failure to produce trachoma in blind human eyes with the various types of bacteria, including Bacterium granulosis, found on the trachomatous conjunctiva was recorded in previous reports.¹ The conclusion was reached that trachoma is not a bacterial disease and the suggestion made that the etiologic agent might be found among the group of so-called filtrable viruses.

That a virus may be the agent in trachoma is suggested by the following observations : (1) the absence of a known bacterial cause, (2) the positive filtrations reported by Nicolle, Cuénod, and Blaizot² and (3) the presence of Halberstaedter-Prowazek³ cytoplasmic inclusion bodies in the conjunctival epithelial cells.

Filtration experiments in trachoma have for the most part given negative results. The positive ones of Nicolle and his associates must be considered of significance, however, since the factor of adsorption of virus by pore surfaces, disregarded in all other experiments on . . . [Full Text PDF of this Article]

Author Affiliations
IOWA CITY

From the Department of Ophthalmology, College of Medicine, State University of Iowa.