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Patrick De Potter, MD; Carol L. Shields, MD; Jerry A. Shields, MD; Adam E. Flanders, MD
Philadelphia, Pa

Arch Ophthalmol. 1995;113(5):556.

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In reply

We acknowledge Drs Ferris and Bloom for their comments on our article.¹ The characteristic appearance of uveal melanoma as hyperintense on T₁-weighted images and hypointense on T₂-weighted images has been reported to occur in 75% to 95% of cases.^1-3 In these reports, the 121 uveal melanomas were evaluated at 1.5 T. It is important to realize that the 11 cases reported in Bloom et al's series⁴ were evaluated at 0.5 T. Therefore, some caution should be advised when interpreting the experience of Bloom and associates regarding the disparate appearance of uveal melanoma and their statement that only 20% of uveal melanomas demonstrated "characteristic" hyperintensity on T₁-weighted images and hypointensity on T₂-weighted images at 0.5 T.

We agree with Ferris and coworkers⁵ that there was no statistical correlation between tumor signal intensity and the degree of tumor . . . [Full Text PDF of this Article]

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