This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (39)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

The Risk for Emerging Resistance to Vancomycin

Eduardo C. Alfonso, MD; Harry W. Flynn, Jr, MD

Arch Ophthalmol. 1995;113(11):1369-1370.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To REDUCE THE RISK for postoperative endophthalmitis, the use of antibiotics in the intraocular irrigating fluid during routine intraocular surgery has been recommended.^1,2 Theoretically, these antibiotics reduce the risk for endophthalmitis, but there are no large randomized prospective studies comparing the use of irrigating fluid antibiotics vs a placebo in reducing the incidence of postoperative endophthalmitis.

Endophthalmitis can occur in spite of using antibiotics in the irrigating fluid. In an in vitro model, it was demonstrated that exposure to antibiotics for a short period of time generally has no effect on organisms commonly responsible for endophthalmitis.³ In clinical practice, endophthalmitis has occurred, for example, in pars plana vitrectomy despite antibiotics in the irrigating fluid. (David Fischer, MD, oral communication, 1995). We have treated one patient with postoperative endophthalmitis after uncomplicated phacoemulsification in which vancomycin hydrochloride was used in the intraocular irrigating fluid. The surgeon must recognize that the . . . [Full Text PDF of this Article]

Author Affiliations
Miami, Fla

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?