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Steven I. Rosenfeld, MD; Jan W. Kronish, MD; Wayne A. Schweitzer, MD; Jeffrey E. Siegal, MD
Delray Beach, Fla

Arch Ophthalmol. 1995;113(1):20-21.

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Anterior scleritis is a serious, potentially sight-threatening inflammatory disease that may present in diffuse, nodular, or necrotizing forms. Topical corticosteroid treatment is often inadequate, and patients with this condition require systemic non-steroidal anti-inflammatory drugs, corticosteroids, or immunosuppressive agents.¹ Systemic cyclosporine has been successfully used for treating severe scleritis, but significant nephrotoxicity, hypertension, hepatoxicity, tremor, hirsutism, and gingival hyperplasia have been associated with its use.^1,2 Recently, topical cyclosporine has been reported to be of benefit in various eye diseases, including scleritis,² and we now report another case.

Report of a Case.

We examined a 68-year-old white woman with a 6-week history of an inflamed right eye that had not responded to a regimen of topical prednisolone acetate and flurbiprofen sodium (0.03%), along with oral indomethacin (25 mg three times a day). She was found to have a large, inflamed superonasal scleral nodule with reactive ptosis (Figure 1). Her . . . [Full Text PDF of this Article]

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