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Fulton Wong, PhD

Arch Ophthalmol. 1993;111(6):754-756.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Retinitis pigmentosa (RP) is a group of hereditary eye diseases, characterized by retinal degeneration, that have no known cure.¹ The prevalence of RP is approximately one in 3000 persons worldwide. The initial symptom of RP is night blindness that usually begins during adolescence. Patients next experience constricted visual fields and eventually a profound loss of peripheral vision. In the course of the eye's deteriorating condition, abnormal pigmentation characteristically accumulates, starting usually in the midperipheral retina. Typically by middle age, the patients are legally blind. The pattern of RP recurrence in an individual's family indicates whether the genetic type is X-linked, recessive, or dominant.¹

Ideally, research in RP treatment should begin when all the variations on the pathogenic chain of events resulting in the phenotype have been identified. Although RP research has not arrived at this point, a considerable body of knowledge about some of the critical cellular and . . . [Full Text PDF of this Article]

Author Affiliations
Durham, NC

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