
The Therapeutic Use of Zinc in Macular Degeneration-Reply
David A. Newsome, MD
New Orleans, La
Arch Ophthalmol. 1989;107(12):1723-1724.
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In Reply.
—The comments of Yuzbasiyan-Gurkan and Brewer concerning their clinical experiences with the relative safety of long-term oral zinc administration are illuminating. It is reasonable to recommend the consumption of a zinc preparation with less potential for gastric irritation so that the supplement may be taken at a time when its absorption is promoted. Additional supplementation with 1 mg of copper daily also appears reasonable.
Yuzbasiyan-Gurkan and Brewer alluded to the variability of zinc uptake. This would likely be a problem regardless of the type of preparation. It is suspected, but not known with certainty, that the absorption of trace minerals may vary with age, as it does with a variety of disease processes. More needs to be understood concerning this matter.
A single trace metal nutrient does not exist in vivo in isolation. It participates in metabolic and functional links involving a variety of other elements. It seems
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