This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Maureen G. Maguire, PhD
Collaborative Corneal Transplantation Studies Baltimore

Arch Ophthalmol. 1988;106(7):877.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—Transmission of cytomegalovirus (CMV) from infected donors to recipients is a serious concern in the transplantation of bone marrow, kidneys, and other vascularized organs. Because the immune systems of these recipients are severely compromised by cytotoxic drug and systemic steroid therapies, primary or secondary infection with CMV may cause a variety of clinical diseases, such as hepatitis, pneumonitis, and retinitis. Usually, serologic testing of corneal donors and recipients for antibodies to CMV is not performed. However, when presented with a positive serologic test result from a multiple organ donor, the corneal surgeon may feel uncomfortable in accepting a cornea for transplantation into a patient whose serologic CMV status is unknown. In fact, we know of at least two instances in which tissue was refused by a corneal surgeon solely on the basis of a positive CMV test result from the donor. Since seropositivity in the general population . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?