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Patrick J. Caskey, MD; James C. Folk, MD
Iowa City

Arch Ophthalmol. 1987;105(4):454.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.

—We read with interest the recent articles by Drs Conway and Campochiaro¹ and McDonald et al² concerning retinal toxicity from intravitreal gentamicin injection as well as the follow-up letters^3,4 in the December 1986 issue of the ARCHIVES regarding the accuracy of prepared gentamicin solutions. Noske's³ letter raised concerns that there may be variability in the dilution of gentamicin solutions prior to their intravitreal injection. Some of the final dilutions may then have unsuspectedly high concentrations of antibiotics, which could contribute to retinal damage.

For the past several years, we have used Garamycin Intrathecal, produced by the Schering Corp, Kenilworth, NJ, for our intravitreal injections. Each milliliter of this solution contains 2.0 mg of gentamicin solution and 8.5 mg of sodium chloride, resulting in the appropriate concentration (200 µg per 0.1 mL) for intravitreal injection. As such, no dilutions are required from the standard . . . [Full Text PDF of this Article]

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