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John T. Thompson, MD; Bert M. Glaser, MD
Baltimore

Arch Ophthalmol. 1985;103(8):1112-1113.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In Reply.

— Dr Wand suggests that the intact anterior hyaloid membrane face may be a barrier to the movement of macromolecules from the vitreous to aqueous in addition to the posterior capsule and lens-zonular diaphragm. We cannot determine the relative contributions of the vitreous, anterior hyaloid membrane, and posterior capsule and zonules as a barrier to the movement of macromolecules from the vitreous to aqueous in our rabbit model. The strength of the hyaloideocapsular ligament in the rabbit makes a rent in the anterior hyaloid membrane very likely when a posterior capsulotomy is performed. We have considered isolating the posterior capsule and testing the diffusion of macromolecules across the posterior capsule in a Boyden chamber, as suggested by Wand, but have found this technique difficult in the rabbit, given the strong attachment of the anterior hyaloid membrane to the posterior capsule.

A recent study by Poliner and associates¹ . . . [Full Text PDF of this Article]

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