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Curtis E. Margo, MD

Arch Ophthalmol. 1985;103(11):1643.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

There is compelling evidence that the acquired immunodeficiency syndrome (AIDS) is caused by a retrovirus known as human T-cell lymphotropic virus type III (HTLV-III) or lymphadenopathy-associated virus.^1,2 An enzyme-linked immunosorbent assay (ELISA) is available to detect antibodies to HTLV-III. Epidemiologic studies using the ELISA test have shown an alarming increase in the prevalence of HTLV-III antibodies among certain highrisk groups. The prevalence of seropositive homosexual men tested in a clinic for the treatment of sexually transmitted disease in San Francisco, for example, has risen from 1% in 1978 to 65% in 1984.³ Persons having hemophilia A are also at risk for AIDS, because factor VIII concentrate is manufactured from pooled plasma. In a study of a California clinic, more than 85% of patients with hemophilia A had antibodies to HTLV-III, presumably as a result of exposure to contaminated blood products.⁴ The full meaning of HTLV-III seropositivity is . . . [Full Text PDF of this Article]

Author Affiliations
Tampa, Fla

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