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Intraocular Pressure FluctuationAn Independent Risk Factor for Glaucoma?
Joseph Caprioli, MD
Arch Ophthalmol. 2007;125(8):1124-1125.
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Prospective, randomized, clinical trials of glaucoma treatment have convincingly shown the efficacy of intraocular pressure (IOP) reduction to slow the progression of glaucomatous optic nerve damage. Prospective, randomized, long-term studies have covered a spectrum of disease from early to late, and from normal to high pressures.1-3 Others included a comparison of medical vs surgical treatment,4 and even treatment vs no treatment.5 All have demonstrated the strength of IOP reduction to slow the progression of disease, as measured by visual function and optic nerve structure. There is no longer any doubt (though some of us never doubted) that robust IOP reduction works in most patients.
A related issue is increasingly being debated. Is IOP fluctuation a separate and independent risk factor for glaucomatous damage? A few caveats are in order. Measurements of IOP may have the appearance of precision, but they are imprecise. Methods of measuring IOP differ, . . . [Full Text of this Article] AUTHOR INFORMATION
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Samin Hong, Gong Je Seong, and Young Jae Hong
Arch Ophthalmol. 2007;125(8):1010-1013.
ABSTRACT
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Intraocular Pressure Fluctuations in Glaucoma
Orzalesi et al.
Arch Ophthalmol 2008;126:745-745.
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