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Robert Phan, BS; Laura Phan, MD; Lawrence E. Ginsberg, MD; George Blumenschein, MD; Michelle D. Williams, MD; Bita Esmaeli, MD

Arch Ophthalmol. 2009;127(8):1074-1075.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Squamous cell carcinoma (SCC) in the periocular region can invade the orbit and intracranial cavity.¹ One route of such spread, known as perineural spread (PNS), involves the contiguous spread of the tumor along the potential space between a nerve and its sheath.^2-6 Perineural spread is associated with a high rate of recurrence, metastasis, and poor prognosis. The usual treatment for SCC with PNS is surgical resection followed by wide-field radiation therapy (RT).⁴ We herein report a case of recurrent SCC with PNS treated with intravenous chemotherapy as a single modality with complete and sustained resolution of clinical and radiographic signs of PNS.

Report of a Case

A 70-year-old man had undergone excision of an invasive SCC (<1 cm wide) of the right cheek with positive excision margins 2 years before the referral. He developed . . . [Full Text of this Article]

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