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Vitreal Seeding From Uveal Melanoma Detected by High-Resolution Spectral-Domain Optical Coherence Tomography
Ludwig M. Heindl, MD;
Christian Y. Mardin, MD;
Leonard M. Holbach, MD;
Gottfried O. H. Naumann, MD;
Friedrich E. Kruse, MD;
Harald L. J. Knorr, MD
Arch Ophthalmol. 2009;127(8):1062-1064.
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High-resolution spectral-domain optical coherence tomography (SD-OCT) is a new exciting technology for visualization of microstructural alterations in retinal diseases.1 We investigated the applicability of this noninvasive method to detect in vivo early vitreous seeding of a histologically proven choroidal melanoma with transretinal tumor extension (Knapp-Rønne melanoma).
Report of a Case
A 68-year-old man had blurred vision and inferotemporal visual field defect of the right eye for 4 months. His visual acuity was 20/30 OD and 20/20 OS. On funduscopy, a large pigmented choroidal mass with overlying hemorrhages was observed in the superonasal quadrant (Figure, A). Subretinal fluid around the tumor and inferior serous retinal detachment were present. Echography revealed a solid mass of 4.8-mm prominence, 11.2 x 10.6 mm2 base, and low homogeneous reflectivity, with a . . . [Full Text of this Article] Comment
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