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Evidence That Anterior Episcleral Nerve Sheath Tumors Arise From the Axenfeld Nerve Loop
Heather S. Chang, MD;
Ben J. Glasgow, MD
Arch Ophthalmol. 2009;127(8):1060-1062.
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The occurrence of solitary episcleral neurofibroma has been described previously in 3 case reports1-4; episcleral schwannomas have been reported 4 times.5-8 The origin of these rare tumors is unknown. However, topographic analysis from our case and those in the literature provides evidence that most anterior scleral nerve sheath tumors arise from intrascleral nerve loops.
Report of Cases
A 45-year-old woman had a mildly tender, white nodule of a few weeks' duration that was adherent to the sclera, measuring 3.5 x 3.5 mm in surface dimension and located approximately 4 mm from the limbus in the inferotemporal quadrant. Neither prior eye operations nor traumatic injury occurred in this region. Microscopic examination of histologic sections revealed a spindle cell tumor with features of a nerve sheath tumor (Figure). The tumor did appear encapsulated.
Figure appears in full text version.
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