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Ana-Maria Oliva, MD; Peter R. Pavan, MD; Curtis E. Margo, MD, MPH; Scott E. Pautler, MD

Arch Ophthalmol. 2009;127(6):822-823.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Mannose-binding lectin (MBL) is an acute-phase reactant that binds microbial surface carbohydrates and participates in opsin-mediated phagocytosis. An important component of the innate immune system, MBL also activates the lectin complement pathway.¹ Low serum levels of MBL have been associated with serious bacterial, fungal, and viral infections.² We describe an otherwise healthy man with MBL deficiency and recalcitrant Candida endophthalmitis.

Report of a Case

A 43-year-old man of Middle Eastern descent had a 1-week history of blurred vision in the right eye. He and several siblings had a history of recurrent oral thrush but no diagnosed immunodeficiency. He had no history of intravenous drug abuse or recent symptoms of oral thrush. On examination, vision in the affected eye was 20/200. A 1.5-mm focal white retinal infiltrate was seen along the superior-temporal arcade with neurosensory macular detachment. He was . . . [Full Text of this Article]

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