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Infliximab Therapy for Refractory Uveitis: 2-Year Results of a Prospective Trial
Eric B. Suhler, MD, MPH;
Justine R. Smith, MBBS, PhD;
Tracy R. Giles, BS;
Andreas K. Lauer, MD;
Michael S. Wertheim, MBChB, MRCOphth;
Daryl E. Kurz, MD;
Paul A. Kurz, MD;
Lyndell Lim, MBBS;
Friederike Mackensen, MD;
Terri D. Pickard, COT;
James T. Rosenbaum, MD
Arch Ophthalmol. 2009;127(6):819-822.
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During the last decade, tumor necrosis factor blockers have become well accepted as useful agents in the armamentarium of treatments for refractory uveitis.1-2 Of the 3 commercially available tumor necrosis factor blockers, published reports suggest that infliximab (Remicade) is more effective for the treatment of uveitis than etanercept (Enbrel),3 although to our knowledge head-to-head randomized studies have not been performed. There is a relative paucity of published experience on the use of the third drug, adalimumab (Humira). Several retrospective studies have reported benefits using infliximab for uveitis.1-3 In 2005, we published preliminary results from the first 23 patients enrolled in our prospective trial of infliximab . . . [Full Text of this Article]Methods
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