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Relentless Placoid Chorioretinitis Associated With Central Nervous System Lesions Treated With Mycophenolate Mofetil
Steven Yeh, MD;
Julie C. Lew, MD;
Wai T. Wong, MD, PhD;
Robert B. Nussenblatt, MD, MPH
Arch Ophthalmol. 2009;127(3):341-343.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Relentless placoid chorioretinitis (RPC) is characterized by retinal lesions similar in clinical and angiographic appearance to acute posterior multifocal pigment placoid epitheliopathy (APMPPE) and serpiginous choroidopathy but differing in its widespread distribution, the numerous lesions typically seen, and the rapidly progressive clinical course.1-2 No consistent systemic manifestations have been described in prior reports. We describe a patient with RPC accompanied by central nervous system (CNS) lesions requiring immunosuppressive medication to achieve disease remission.
Report of a Case
A 20-year-old man had a 3-week history of an enlarging central scotoma in the left eye, followed by similar symptoms in the right eye. He denied any viral prodrome but reported a history of migraines. Visual acuity at the initial visit was 20/400 OD and 20/50 OS. Ophthalmic examination revealed white placoid lesions within the posterior pole resembling APMPPE, with . . . [Full Text of this Article] Comment
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