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Sashank K. Reddy, PhD; Cristian M. Salgado, MD; David G. Hunter, MD, PhD

Arch Ophthalmol. 2009;127(3):337-338.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In 1935, Bielschowsky¹ described a syndrome in which the ability to fuse 2 images was lost because of a long-standing sensory deprivation. The main symptom was intractable diplopia following the removal of the cause of sensory deprivation. Bielschowsky called this syndrome horror fusionis. This syndrome, now known as acquired central fusion disruption, has been reported following cataract extraction,² aphakia,³ severe head trauma,⁴ and brain surgery.⁵ We report 2 cases of central fusion disruption that developed after irradiation to the pineal area.

Report of Cases

Case 1

A 12-year-old boy had a chief symptom of double vision. One month earlier, the patient had visited a neurologist for headaches and visual disturbances. A biopsy obtained during a third ventriculostomy demonstrated a pineal region tumor consistent with germinoma. He subsequently received radiation therapy of 2550 cGy (the conversion of centigray to rad is 1:1) with . . . [Full Text of this Article]

Case 2

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