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  Vol. 127 No. 1, January 2009 TABLE OF CONTENTS
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Rationale for Adjunctive Topical Corticosteroids in Bacterial Keratitis

Holly B. Hindman, MD; Sheel B. Patel, MD; Albert S. Jun, MD, PhD

Arch Ophthalmol. 2009;127(1):97-102.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Bacterial keratitis is a major cause of vision loss worldwide.1 Despite the development of newer broad-spectrum antibiotics, the scope of the problem appears to have grown in the United States, where the incidence of ulcerative keratitis was found in a community-based study to have increased by 435% from 1950 to 1988.2 This rise may have been secondary to prior underreporting of bacterial keratitis but notably also occurred during a period of growth of 1 important risk factor: contact lens wear.3

Data that are more recent indicate that bacterial keratitis remains a significant public health problem, particularly among contact lens wearers. In 1990, the estimated total US incidence of bacterial keratitis was 27 000 cases.2 Forster4 reviewed 28 years (1969-1997) of ocular microbiology files in Miami and noted an incidence rate of 3.1 cases of suspected bacterial keratitis per . . . [Full Text of this Article]

ETIOLOGY


RISK FACTORS FOR INFECTION AND POOR OUTCOME

PATHOGENESIS
Role of the Microbe

Host Response

Microbe Host Interaction


GOALS OF TREATMENT

ROLE OF CORTICOSTEROIDS

EVIDENCE

RECOMMENDATIONS

CONCLUSIONS

AUTHOR INFORMATION
Author Affiliations: Cornea and Anterior Segment Service, The Wilmer Eye Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland.



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The Steroid Controversy in Bacterial Keratitis
Acharya et al.
Arch Ophthalmol 2009;127:1231-1231.
FULL TEXT  





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