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-3 Long-Chain Polyunsaturated Fatty Acid Intake Inversely Associated With 12-Year Progression to Advanced Age-Related Macular Degeneration

John Paul SanGiovanni, ScD; Elvira Agrón, MA; Traci E. Clemons, PhD; Emily Y. Chew, MD

Arch Ophthalmol. 2009;127(1):110-112.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Age-related macular degeneration (AMD) is a leading cause of vision loss. Age-Related Eye Disease Study (AREDS) participants reporting the highest intake of -3 long-chain polyunsaturated fatty acids (LCPUFAs) were approximately half as likely as their peers reporting the lowest intake of these nutrients to have neovascular (NV) AMD¹ at baseline or to progress across a 6-year period from bilateral drusen to central geographic atrophy (CGA).² The Age-Related Eye Disease Study provides data that represent, to our knowledge, the largest longitudinal sample collected and classified with standardized methods as part of a natural history study on AMD. We now report that our baseline and 6-year findings persisted in 12-year AMD incidence models. These results are consistent with existing data.^3-4

Methods

The Age-Related Eye Disease Study was a National Institutes of Health–sponsored and administered multicenter study designed to . . . [Full Text of this Article]

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